This Easy Pepperoni Bread is made with homemade pizza dough and stuffed with mozzarella cheese and tons of pepperoni. It gets rolled up into a loaf and baked until golden brown and bubbly! Serve with a side of marinara sauce for dipping!

author picking up a slice of pepperoni bread
Kelley Simmons Kelley’s Tips

Before You Get Started

  • Use Store-Bought Dough. Short on time? Grab pizza dough from the store and follow the remaining steps as directed.
  • Finish with Garlic Butter. For a garlic bread twist, brush the hot loaf with melted butter and sprinkle with garlic powder and Parmesan cheese right after baking.
  • Switch Up the Cheese. Mozzarella is classic, but provolone, Parmesan, Swiss, or cheddar all work beautifully. Use what you have on hand.
  • Sprinkle cornmeal on baking pan. This helps it not to stick to the pan, adds crunch and flavor!
  • Expect Some Cheese Escape. A little melted cheese bubbling out is totally normal (and delicious). Those crispy bits on the pan are the best part!
  • Change the Fillings. Swap pepperoni for salami, spicy sausage, or other Italian meats. You can even try shredded crockpot barbecue chicken for a fun twist.
Kelley

Pepperoni Bread Ingredients

ingredients for homemade pepperoni bread on counter
  • Warm Water – Activates the yeast and gets the dough rising. It should feel warm to the touch, not hot.
  • Instant Dry Yeast – Helps the dough rise quickly and creates a soft, fluffy texture.
  • Honey – Feeds the yeast and adds a subtle touch of sweetness to balance the savory filling.
  • Olive Oil – Adds flavor and keeps the dough tender.
  • Salt – Enhances the overall flavor of the bread.
  • All-Purpose Flour – Builds the structure of the dough. Start with less and add more as needed until the dough is soft but not sticky.
  • Shredded Mozzarella – Creates that irresistible gooey, stretchy cheese pull everyone loves.
  • Pepperoni – Adds savory, slightly spicy flavor throughout the loaf.
  • Marinara Sauce – Perfect for dipping and gives it that classic pizza-style finish.

How to Make Pepperoni Bread

  • Make the Pizza Dough: Add warm water to the bowl of the stand mixer with the dough hook attachment. Add in yeast and honey. Stir and allow it to rest for 5 minutes. Add 2 cups of flour, salt, and oil. Mix to combine, 3-4 minutes on low speed. Slowly add remaining 1/2-1 cup of flour or until a smooth ball forms that pulls cleanly away from the sides of the bowl.
  • Rest: Cover bowl with plastic wrap and allow the dough to rest for 1 hour.
  • Roll and Assemble: Roll dough into a rectangle roughly 14” x 22”. Spread with the shredded mozzarella, then top with the pepperoni. Starting from the longer side, roll into a log then place on a greased baking sheet. With a very sharp knife score the top of the bread to release the steam as it bakes.
  • Bake: Place in oven and bake at 400°F for 25 minutes or until golden brown on the outside.
  • Serve: Allow to cool for 10 minutes before slicing. Serve with slow cooker tomato sauce or homemade ranch dressing for dipping and enjoy!
step by step pictures of how to make homemade pepperoni bread

Pepperoni Bread FAQ

How can I keep my pepperoni bread from getting soggy?

Avoid adding sauce inside the loaf. It’s best to serve marinara on the side for dipping.

How can I make this ahead of time?

You can assemble the loaf, cover tightly, and refrigerate for several hours before baking. Let it sit at room temperature for about 20–30 minutes before putting it in the oven.

How do I prevent the cheese from leaking out?

Roll the dough tightly and pinch the seams well before baking. A little cheese bubbling out is totally normal though!

If you love pizza then you will love my High Protein Pizza Muffins!

Looking for more Appetizer Recipes? Try my Easy Toasted Ravioli, Crispy Baked Chicken Wings, or my Ham and Cheese Pinwheels.

Storage, Reheating and Freezing Instructions

  • Store: The pepperoni pizza bread in an airtight container in the refrigerator for up to 3 days.
  • Freeze: This bread freezes really well! Store in an airtight container and freeze for up to 4 months.
  • To Reheat: From frozen allow the bread to thaw for 1-2 hours at room temperature then heat them in the oven or toaster oven at 350ºF until warmed through. You can also reheat in the microwave until warm.

Looking for more Appetizer Recipes? Try my Easy Toasted Ravioli, Crispy Baked Chicken Wings, or my Ham and Cheese Pinwheels.

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    Recipe

    Pepperoni Bread

    4.74 from 15 votes
    This Easy Pepperoni Bread is made with homemade pizza dough and stuffed with mozzarella cheese and tons of pepperoni. It gets rolled up into a loaf and baked until golden brown and bubbly! Serve with a side of marinara sauce for dipping!
    Prep Time: 20 minutes
    Cook Time: 25 minutes
    Rising Time: 1 hour
    Total Time: 1 hour 45 minutes
    Serves 8

    Ingredients 

    • 1 cup water , (heated to 110°F)
    • 2 ¼ tsp instant dry yeast
    • 2 tsp honey
    • tbsp olive oil
    • 1 tsp salt
    • 2½-3 cups all purpose flour
    • 3 cups shredded mozzarella
    • 6 ounce package of pepperoni
    • marinara sauce for dipping, if desired

    Instructions

    • Add warm water to the bowl of the stand mixer with the dough hook attachment. Add in yeast and honey. Stir and allow it to rest for 5 minutes.
    • Add 2 cups of flour, salt, and oil. Mix to combine, 3-4 minutes on low speed. Slowly add remaining 1/2-1 cup of flour or until a smooth ball forms that pulls cleanly away from the sides of the bowl.
    • Cover bowl with plastic wrap and allow the dough to rest for 1 hour.
    • Preheat oven to 400°F. Roll dough into a rectangle roughly 14'' x 22''. Spread with the shredded mozzarella, then top with the pepperoni.
    • Starting from the longer side, roll into a log then place on a greased baking sheet. With a very sharp knife score the top of the bread to release the steam as it bakes.
    • Bake for 25 minutes or until golden brown on the outside.
    • Allow to cool for 10 minutes before slicing. Serve with marinara sauce for dipping and enjoy!

    Notes

    • Sprinkle cornmeal on baking pan. This helps it not to stick to the pan, adds crunch and flavor!
     

    Nutrition Information

    Calories: 413kcalCarbohydrates: 34gProtein: 20gFat: 22gSaturated Fat: 9gCholesterol: 56mgSodium: 933mgPotassium: 165mgFiber: 2gSugar: 2gVitamin A: 284IUVitamin C: 1mgCalcium: 223mgIron: 2mg

    Did You Make This?

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